Complications
Common in severe disease with or without frank shock due to dehydration and ongoing fluid losses through vomiting and diarrhoea as well as poor oral intake and possible haemorrhage.[13]
Nearly half of Ebola virus disease survivors in one study from Sierra Leone reported difficulty concentrating at follow-up visits.[69] This may apply to Marburg virus disease survivors as well.
Has been reported in severe disease. May be caused by dehydration initially, but may be a consequence of disseminated intravascular coagulation or direct damage to the kidneys by Marburg virus in later stages.[27] Early recognition by monitoring urine output and blood biochemistry enables prompt action to be taken.
14% to 60% of Ebola virus disease survivors reported ocular symptoms including eye pain, clear discharge, red eyes, and blurred vision, or were found to have uveitis at follow-up visits.[64][65] This has been found in Marburg virus disease survivors as well.[13] The central nervous system and globe are thought to be filovirus sanctuary sites where disease can be persistent.[18]
Headache, confusion, seizures, memory loss, headaches, cranial nerve abnormalities, and tremor may occur, and neurological symptoms have been documented in both acute illness and among Ebola virus survivors.[66] The central nervous system and globe are thought to be filovirus sanctuary sites where disease can be persistent.[18]
75% of Ebola virus disease survivors reported lethargy or fatigue at follow-up visits.[67] This may apply to Marburg virus disease survivors as well.
Psychological distress was common among Ebola virus disease survivors in the 2014 to 2016 West Africa Ebola virus disease outbreak.[68] Exposure to death in the treatment units and stigma in the community induced post-traumatic stress reactions and symptoms of depression.[68] These symptoms are also common among Marburg virus disease survivors, and would be expected to be especially prevalent in outbreak settings.[13]
Nearly all Ebola virus disease survivors in one study from Sierra Leone reported anorexia at follow-up visits.[69] This may apply to Marburg virus disease survivors as well.
Asthenia has been reported among Marburg disease survivors.[13]
38% of Ebola virus disease survivors in the United States reported paraesthesias or dysaesthesia at follow-up visits.[67] This may apply to Marburg virus disease survivors as well.
Use of this content is subject to our disclaimer