Necrotising fasciitis

Mortality from necrotising fasciitis properly treated with surgery plus antibiotics has been estimated at between 10% and 40%. Mortality is higher in patients who develop shock and end-organ damage, approaching 50% to 70%.[2]Stevens DL, Bisno AL, Chambers HF, et al. Practice guidelines for the diagnosis and management of skin and soft tissue infections: 2014 update by the Infectious Diseases Society of America. Clin Infect Dis. 2014 Jul 15;59(2):e10-52. https://academic.oup.com/cid/article/59/2/e10/2895845 http://www.ncbi.nlm.nih.gov/pubmed/24973422?tool=bestpractice.com ​

Recurrence of necrotising fasciitis is rare.[1]Pasternack MS, Swartz MN. Cellulitis, necrotizing fasciitis, and subcutaneous tissue infections. In: Bennett JE, Dolin R, Blaser MJ, eds. Mandell, Douglas, and Bennett’s principles and practice of infectious diseases. Philadelphia, PA: Elsevier; 2015:1194-215.[2]Stevens DL, Bisno AL, Chambers HF, et al. Practice guidelines for the diagnosis and management of skin and soft tissue infections: 2014 update by the Infectious Diseases Society of America. Clin Infect Dis. 2014 Jul 15;59(2):e10-52. https://academic.oup.com/cid/article/59/2/e10/2895845 http://www.ncbi.nlm.nih.gov/pubmed/24973422?tool=bestpractice.com ​ However, significant functional and cosmetic morbidity may remain following initial surgical therapies, which may require subsequent reconstruction.