Criteria

The Resuscitation Council (UK) diagnostic criteria for anaphylaxis[32]

Anaphylaxis is likely when all of the following three criteria are met:

  • Sudden onset and rapid progression of symptoms

  • Life-threatening Airway and/or Breathing and/or Circulation problems

  • Skin and/or mucosal changes (flushing, urticaria, angio-oedema).

The following supports the diagnosis:

  • Exposure to a known allergen for the patient.

Remember:

  • Skin or mucosal changes alone are not a sign of an anaphylactic reaction

  • Skin and mucosal changes can be subtle or absent in up to 20% of reactions (some patients have only a decrease in blood pressure [i.e., a Circulation problem])

  • There can also be gastrointestinal symptoms (e.g., vomiting, abdominal pain, incontinence).

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