Research Methods & Reporting
AMSTAR 2: a critical appraisal tool for systematic reviews that include randomised or non-randomised studies of healthcare interventions, or both
BMJ 2017; 358 doi: https://doi.org/10.1136/bmj.j4008 (Published 21 September 2017) Cite this as: BMJ 2017;358:j4008
Data supplement
Web extra
- Data Supplement - Supplementary figure: the AMSTAR 2 instrument
- Data Supplement - Supplementary appendix 1: AMSTAR 2 guidance document
- Data Supplement - Supplementary appendix 2: Inter-rater reliability of AMSTAR 2 items and references for studies included in the analyses
Web extra
- Data Supplement - Supplementary figure: the AMSTAR 2 instrument
- Data Supplement - Supplementary appendix 1: AMSTAR 2 guidance document
- Data Supplement - Supplementary appendix 2: Inter-rater reliability of AMSTAR 2 items and references for studies included in the analyses
Related articles
- Research Methods & Reporting Published: 05 February 2010; BMJ 340 doi:10.1136/bmj.c221
- Education And Debate Published: 03 September 1994; BMJ 309 doi:10.1136/bmj.309.6954.597
- Research Methods & Reporting Published: 12 October 2016; BMJ 355 doi:10.1136/bmj.i4919
- Paper Published: 29 May 2003; BMJ 326 doi:10.1136/bmj.326.7400.1167
- Research Methods & Reporting Published: 18 October 2011; BMJ 343 doi:10.1136/bmj.d5928
- Research Published: 16 July 2010; BMJ 341 doi:10.1136/bmj.c3515
- Education And Debate Published: 10 January 1998; BMJ 316 doi:10.1136/bmj.316.7125.140
- Research Methods & Reporting Published: 15 September 2020; BMJ 370 doi:10.1136/bmj.m2864
- Research Published: 07 October 2020; BMJ 371 doi:10.1136/bmj.m3502
- Research Methods & Reporting Published: 29 March 2021; BMJ 372 doi:10.1136/bmj.n71
- Research Methods & Reporting Published: 29 March 2021; BMJ 372 doi:10.1136/bmj.n160
- Research Published: 19 April 2021; BMJ 373 doi:10.1136/bmj.n736
- Analysis Published: 25 February 2022; BMJ 376 doi:10.1136/bmj-2021-067475
- Research Published: 29 June 2022; BMJ 377 doi:10.1136/bmj-2021-068743
- Research Published: 13 July 2022; BMJ 378 doi:10.1136/bmj-2021-069445
- Opinion Published: 05 August 2022; BMJ 378 doi:10.1136/bmj.o1740
- Research Published: 09 August 2022; BMJ 378 doi:10.1136/bmj-2022-070849
- Clinical Review Published: 16 January 2023; BMJ 380 doi:10.1136/bmj-2022-072398
- Research Published: 01 February 2023; BMJ 380 doi:10.1136/bmj-2022-072415
- Research Published: 30 August 2023; BMJ 382 doi:10.1136/bmj-2022-072348
- Research Published: 20 December 2023; BMJ 383 doi:10.1136/bmj-2023-077166
- Research Methods & Reporting Published: 06 February 2024; BMJ 384 doi:10.1136/bmj-2023-076335
- Research Published: 28 February 2024; BMJ 384 doi:10.1136/bmj-2023-077310
- Research Published: 22 January 2025; BMJ 388 doi:10.1136/bmj-2024-081164
- Research Methods & Reporting Published: 18 March 2025; BMJ 388 doi:10.1136/bmj-2024-079839
See more
- Introductory AddressProv Med Surg J October 03, 1840, s1-1 (1) 1-4; DOI: https://doi.org/10.1136/bmj.s1-1.1.1
- Report of the Meeting of the Eastern Branch of the Provincial Association at Bury St. Edmond'sProv Med Surg J October 03, 1840, s1-1 (1) 10-13; DOI: https://doi.org/10.1136/bmj.s1-1.1.10
- Mr. Warburton's Bill for the Regulation of the Medical ProfessionProv Med Surg J October 03, 1840, s1-1 (1) 13-15; DOI: https://doi.org/10.1136/bmj.s1-1.1.13
- An Atlas of Plates, illustrative of the Principles and Practice of Obstetric Medicine and Surgery, with descriptive LetterpressProv Med Surg J October 03, 1840, s1-1 (1) 4; DOI: https://doi.org/10.1136/bmj.s1-1.1.4
- A Practical Treatise on the Diseases peculiar to Women, illustrated by Cases, &cProv Med Surg J October 03, 1840, s1-1 (1) 4-5; DOI: https://doi.org/10.1136/bmj.s1-1.1.4-a
Cited by...
- Effectiveness of biologics for patients with severe asthma: study protocol for an umbrella review of systematic reviews and meta-analyses
- Iron deficiency in patients with cardiogenic shock: protocol for a scoping review
- Agreeability testing of AMSTAR-PF, a tool for quality appraisal of systematic reviews of prognostic factor studies
- Psychotherapies for adults with complex presentations of PTSD: a clinical guideline and five systematic reviews with meta-analyses
- Identifying predictors of neuropathic pain medication prescribing, adherence, and discontinuation: a systematic review and meta-analysis
- Early versus late tracheostomy in critically ill patients: an umbrella review of systematic reviews of randomised clinical trials with meta-analyses and trial sequential analysis
- Risk of Bias in Network Meta-Analysis (RoB NMA) tool
- Rapid review method series: interim guidance for the reporting of rapid reviews
- Methodological and statistical characteristics of meta-analyses on spinal cord stimulation for chronic pain: a systematic review
- The health beliefs, attitudes, and intentions of males toward pregnancy planning and preconception health and care: a systematic review
- Prevention of mental disorders after exposure to natural hazards: a meta-analysis
- Cardiorespiratory fitness and health in children and adolescents: an overview of systematic reviews with meta-analyses representing over 125 000 observations covering 33 health-related outcomes
- Improving peer review of systematic reviews and related review types by involving librarians and information specialists as methodological peer reviewers: a randomised controlled trial
- Self-determination theory in physiotherapy practice: A rapid review of randomized controlled trials and systematic reviews
- Effectiveness of exercise for improving cognition, memory and executive function: a systematic umbrella review and meta-meta-analysis
- Supplemental oxygen for symptomatic relief in people with serious respiratory illness: a systematic review and meta-analysis
- Effectiveness of pharmacological and non-pharmacological interventions for treatment-resistant depression in older patients: a systematic review and meta-analysis
- Umbrella Review on the Relationship Between Vitamin D Intake and Cancer
- Safety and efficacy of tirofiban versus traditionaldualantiplatelettherapy in endovasculartreatment of intracranialaneurysms: asystematicreview and meta-analysis
- Development of an Australian Clinical Practice Guideline on methylenedioxymethamphetamine (MDMA)-assisted Psychotherapy for Post-traumatic Stress Disorder
- Effectiveness of clinical healthcare interventions for enhancing the work participation of patients with various health conditions: a synthesis of systematic reviews
- Gender, race and ethnicity biases experienced by hospital physicians: an umbrella review to explore emerging biases in the evidence base
- Prise en charge du trouble lie a lusage dopioides : mise a jour 2024 du guide de pratique clinique nationale
- Physical and psychological factors related to injury, illness and tactical performance in law enforcement recruits: a systematic review
- Relative efficacy of prehabilitation interventions and their components: systematic review with network and component network meta-analyses of randomised controlled trials
- Interventions to prevent violence against women and girls globally: a global systematic review of reviews to update the RESPECT women framework
- Systematic review of reviews on interventions to engage men and boys as clients, partners and agents of change for improved sexual and reproductive health and rights
- Evaluating the utility of large language models in generating search strings for systematic reviews in anesthesiology: a comparative analysis of top-ranked journals
- Artificial Intelligence in Pancreatic Intraductal Papillary Mucinous Neoplasm Imaging: A Systematic Review
- Risk factors for brain metastasis in lung cancer: an umbrella review of systematic reviews and meta-analyses
- Relationship between staff experience and patient outcomes in hospital settings: an overview of reviews
- Efficacy of esketamine for chronic post-thoracotomy pain: protocol for a systematic review and meta-analysis
- Specialist clinical pathways in audiology services for adults living with coexisting hearing loss and dementia: a scoping review protocol
- Mifepristone as a non-emergency contraceptive among women of reproductive age: a protocol for systematic review and meta-analysis
- Multisectoral One Health collaborations across human, animal and environmental health: a protocol paper for an umbrella systematic review of conceptual and analytical approaches to sustainability
- Guidelines for the development and validation of patient-reported outcome measures: a scoping review
- Efficacy and safety of therapies for Stills disease and macrophage activation syndrome (MAS): a systematic review informing the EULAR/PReS guidelines for the management of Stills disease
- Acupuncture for cancer-related insomnia: systematic review and meta-analysis of randomised controlled trials
- Update from 2010 (standard operating procedure): protocol for the 2024 British Society of Gastroenterology Guidelines on colorectal surveillance in inflammatory bowel disease
- Association between physician burnout and patient safety: study protocol for an overview of systematic reviews and meta-analyses
- Appraised evidence and decision making in clinical practice
- Risk prediction tools for pressure injury occurrence: An umbrella review of systematic reviews reporting model development and validation methods
- Management of opioid use disorder: 2024 update to the national clinical practice guideline
- Updating the critical steps of the quality implementation framework: a protocol for an umbrella review of reviews
- The efficacy of valproate in acute mania, bipolar depression and maintenance therapy for bipolar disorder: an overview of systematic reviews with meta-analyses
- Mechanisms of end-of-life communication contributing to optimal care at the end of life: a review of reviews
- Effectiveness and clinical relevance of kinesio taping in musculoskeletal disorders: a protocol for an overview of systematic reviews and evidence mapping
- Breathing techniques to reduce symptoms in people with serious respiratory illness: a systematic review
- The Effect of Psychotherapy in the Management of Obesity: An umbrella review
- A European clinical practice guideline on pain, agitation, delirium, and iatrogenic withdrawal syndrome management in critically ill children: A protocol
- Metronomic chemotherapy for paediatric extracranial solid tumours: a systematic review and meta-analysis of randomised clinical trials
- Botulinum toxin for the management of bruxism: an overview of reviews protocol
- The effect of graded exercise therapy on fatigue in people with serious respiratory illness: a systematic review
- Objectively measured daily steps and health outcomes: an umbrella review of the systematic review and meta-analysis of observational studies
- Dupuytrens disease and occupational mechanical exposures: a systematic review and meta-analysis
- Accuracy and clinical effectiveness of risk prediction tools for pressure injury occurrence: An umbrella review
- Impact of the degree of synergy between patient and nurse perceptions on the clinical outcome of pressure injury prevention: a mixed-methods systematic review protocol
- Organisational models for managing Public Health Emergencies of International Concern (PHEICs) in the South-East Asia Region (SEAR) nations: protocol for a systematic review
- Scientific evidence of acupuncture for post-stroke motor impairment: protocol for an overview of systematic reviews and meta-analyses
- Clinical effectiveness of robotic versus laparoscopic and open surgery: an overview of systematic reviews
- A 10 Years Update of Effects of Exercise on Depression Disorders - in otherwise healthy adults: A Systematic Review of Meta-Analyses and Neurobiological Mechanisms
- Gender and sex differences in occupation-specific infectious diseases: a systematic review
- DOSage of Exercise for chronic low back pain disorders (DOSE): protocol for a systematic review with dose-response network meta-analysis
- Methodological quality of research on perioperative immunomodulatory supplementation in oncological gastrointestinal tract surgery: a meta-research protocol
- Development of a core data set for describing, measuring and reporting the learning curve in studies of novel invasive procedures: study protocol
- Perioperative application of chatbots: a systematic review and meta-analysis
- Exploring decision-makers challenges and strategies when selecting multiple systematic reviews: insights for AI decision support tools in healthcare
- Umbrella review of risk factors for inflammatory bowel disease: a study protocol
- Narrative reviews in anesthesia and pain medicine: guidelines for producers, reviewers and consumers
- What is the association between the microbiome and cognition? An umbrella review protocol
- Protocol for the development of a reporting guideline for umbrella reviews on epidemiological associations using cross-sectional, case-control and cohort studies: the Preferred Reporting Items for Umbrella Reviews of Cross-sectional, Case-control and Cohort studies (PRIUR-CCC)
- Inclusion, characteristics and credibility of systematic reviews in doctoral theses: A cross-sectional study of all Medical Faculties in Sweden
- Systematic reviews and meta-analyses in regional anesthesia and pain medicine (Part I): guidelines for preparing the review protocol
- Assessing the methodological quality and risk of bias of systematic reviews: primer for authors of overviews of systematic reviews
- The Pediatric Sleep Questionnaire as a screening tool for sleep-related breathing disorders: An Umbrella Review
- Interventions to promote medical student well-being: an overview of systematic reviews
- Strategies for optimising early detection and obstetric first response management of postpartum haemorrhage at caesarean birth: a modified Delphi-based international expert consensus
- Risk of transmission of HIV to infants during breast/chest feeding when mothers/birthing parents living with HIV are on antiretroviral therapy: a protocol for a rapid review
- Cardiorespiratory fitness is a strong and consistent predictor of morbidity and mortality among adults: an overview of meta-analyses representing over 20.9 million observations from 199 unique cohort studies
- Do pulmonary rehabilitation programmes improve outcomes in patients with COPD posthospital discharge for exacerbation: a systematic review and meta-analysis
- Outcome measures for children with speech sound disorder: an umbrella review
- Community-Partnered Research appraisal tool for conducting, reporting and assessing community-based research
- Benchmarking Human-AI Collaboration for Common Evidence Appraisal Tools
- Comparative accuracy of five screening tools for sarcopenia in community older adults:a systematic review and a network meta-analysis
- Supplements for cognitive ability in patients with mild cognitive impairment or Alzheimers disease: a protocol for systematic review and network meta-analysis of randomised controlled trials
- Effectiveness of metformin to pregnant women with PCOS to reduce spontaneous abortion and gestational diabetes mellitus: a protocol for an overview of reviews
- Inter-reviewer reliability of human literature reviewing and implications for the introduction of machine-assisted systematic reviews: a mixed-methods review
- A cross sectional survey of Australian and New Zealand specialist trainees research experiences and outputs
- Ultra-processed food exposure and adverse health outcomes: umbrella review of epidemiological meta-analyses