Intended for healthcare professionals

  1. Research
  2. Potential impact on...
  3. Potential impact on estimated treatment effects of information lost to follow-up in randomised controlled trials (LOST-IT): systematic review
CCBYNC Open access
Research

Potential impact on estimated treatment effects of information lost to follow-up in randomised controlled trials (LOST-IT): systematic review

BMJ 2012; 344 doi: https://doi.org/10.1136/bmj.e2809 (Published 18 May 2012) Cite this as: BMJ 2012;344:e2809

Data supplement

  • Web Extra

    Extra material supplied by the author

    Files in this Data Supplement:

    • Data Supplement - Appendix 1: Search strategy for Medline
    • Data Supplement - Appendix 2: Explanation and illustrations of assumptions considered
    • Data Supplement - Appendix 3: Regression analysis exploring association of ???percentage of participants lost to follow-up??? and general and methodological trial characteristics
    • Data Supplement - Appendix 4: Sensitivity analyses for potential impact of loss to follow-up reporting percentage of studies losing significance
    • Data Supplement - Appendix 5: Analyses of potential impact of loss to follow-up reporting ratio of relative risk

Related articles

See more

Cited by...

  • SPIRIT 2025 explanation and elaboration: updated guideline for protocols of randomised trials
  • A Multicentre Randomised Controlled Trial Assessing the Efficacy of Antimicrobial Prophylaxis for Extracorporeal Shock Wave Lithotripsy in Reducing Urinary Tract Infection (APPEAL): Statistical Analysis Plan and Methodology
  • Augmenting Fact and Date of Death in Electronic Health Records using Internet Media Sources: A Validation Study from Two Large Healthcare Systems
  • Nutrition users guides: RCTs part 1 - structured guide for assessing risk of bias in randomised controlled trials that address therapy or prevention questions
  • Leveraging Stacked Classifiers for Multi-task Executive Function in Schizophrenia Yields Diagnostic and Prognostic Insights
  • Optimizing Research Data Acquisition with Smart Pill Bottles (SPBs), the ORDAS Trial: A Feasibility and Implementation Study Protocol
  • The SQUEEZE pilot trial: a trial to determine whether septic shock reversal is quicker in pediatric patients randomized to an early goal directed fluid-sparing strategy vs. usual care
  • Factors Associated with the Magnitude Of acUpuncture treatment effectS (FAMOUS): a meta-epidemiological study of acupuncture randomised controlled trials
  • Importance of accounting for loss to follow-up when comparing mortality between immigrants and long-term residents: a population-based retrospective cohort
  • Ross for Valve replacement In AduLts (REVIVAL) pilot trial: rationale and design of a randomised controlled trial
  • Use of patient-reported outcome measures (PROMs) in clinical diabetes consultations: the DiaPROM randomised controlled pilot trial
  • Effectiveness of workplace exercise interventions in the treatment of musculoskeletal disorders in office workers: a protocol of a systematic review
  • Potential impact of missing outcome data on treatment effects in systematic reviews: imputation study
  • US purchases world stocks of remdesivir: why the rest of the world should be glad to be at the back of the queue
  • Having a Primary Care Provider is the Strongest Predictor of Successful Follow-up of Participants in a Clinical Trial
  • Effects of short-term, medium-term and long-term resistance exercise training on cardiometabolic health outcomes in adults: systematic review with meta-analysis
  • Safety and efficacy of perioperative benzodiazepine administration: study protocol for a systematic review and meta-analysis
  • Are perioperative interventions effective in preventing chronic pain after primary total knee replacement? A systematic review
  • Risk of bias assessment of randomised controlled trials referenced in the 2015 American Heart Association guidelines update for cardiopulmonary resuscitation and emergency cardiovascular care: a cross-sectional review
  • Effectiveness of a chronic obstructive pulmonary disease integrated care pathway in a regional health system: a propensity score matched cohort study
  • Early vasopressor use following traumatic injury: a systematic review
  • Surgical ablation of atrial fibrillation: a protocol for a systematic review and meta-analysis of randomised controlled trials
  • Best (but oft-forgotten) practices: intention-to-treat, treatment adherence, and missing participant outcome data in the nutrition literature
  • Reporting of Lost to Follow-Up and Treatment Discontinuation in Pharmacotherapy and Device Trials in Chronic Heart Failure: A Systematic Review
  • Transfusion of fresher vs older red blood cells in hospitalized patients: a systematic review and meta-analysis
  • Reporting missing participant data in randomised trials: systematic survey of the methodological literature and a proposed guide
  • Management of Central Poststroke Pain: Systematic Review of Randomized Controlled Trials
  • Reporting, handling and assessing the risk of bias associated with missing participant data in systematic reviews: a methodological survey
  • Deviation from intention to treat analysis in randomised trials and treatment effect estimates: meta-epidemiological study
  • How to optimize participant retention and complete follow-up in surgical research
  • Interpreting trial results following use of different intention-to-treat approaches for preventing attrition bias: a meta-epidemiological study protocol
  • Systematic review of percutaneous closure versus medical therapy in patients with cryptogenic stroke and patent foramen ovale
  • Positive association between conflicts of interest and reporting of positive results in randomized clinical trials in dentistry
  • SPIRIT 2013 explanation and elaboration: guidance for protocols of clinical trials
Back to top