GMFM-66-IS scores were supported by strong construct validity and moderate responsiveness evidence for use with infants and toddlers at high risk for CP.
This systematic review examined the association and diagnostic accuracy of MRI acquired < 36 weeks postmenstral age to detect cerebral palsy and other adverse motor outcomes at or beyond 3 years corrected age in infants born preterm.
201 infants at risk for developmental disorders were assessed using two General Movements Assessments (GMA) and one Hammersmith Infant Neurological Examination (HINE), integrated into routine follow up care. Developmental outcome was assessed with a neurologic examination at 2 years, and the Bayley Scales of Infant and Toddler Development at 2 - 3.5 years of age. Using a combination of GMA measures and the HINE, CP was predicted with 100% sensitivity, and non-CP delays were predicted with 83%-87% sensitivity. Although specificity was lower, this approach provides a practical method of identifying most infants who will benefit from early intervention therapy, even in countries such as Sri Lanka where access to neuroimaging and specialist care is limited..
Self-injurious behaviour (SIB) is relatively common in children with autism spectrum disorder (ASD) with an estimated prevalence of up to 42%. In those most severely affected there is a risk of life-altering and life-threatening injury to the individual themselves, the impact on caregivers is not well-understood. This study aims to describe the experiences of family caregivers of children with ASD and SIB through the use of qualitative methodology. In-depth semi-structured one-on-one interviews were conducted with 12 family caregivers, transcripts were then analyzed and three main themes were developed. Through our analysis it became clear that SIB is associated with multiple and complex challenges for children and their families. These findings highlight the need to prioritize the development of effective therapies and increased availability of appropriate resources for childern with SIB and their families.
Informed consent in assisted reproductive technology (ART) is a complex, multifaceted process. Given the short- and long-term risks associated with ART, neurodevelopmental physicians can benefit from a better understanding of this process when evaluating patients for neurodevelopmental disability.
Detailed neurobehavioral phenotyping using the neurobehavioral evaluation tool (NET) caregiver-report survey scales was conducted across seven study groups.
This original article is commented by Dieu and Briganti on pages559–560 of this issue.
This study investigates the impact of cerebellar hemorrhage (CBH) and atrophy in extremely preterm infants with intraventricular hemorrhage (IVH) on neurodevelopment at two years of age. Findings reveal that CBH is a significant predictor of impaired cognitive and motor outcomes, with cerebellar atrophy further exacerbating developmental delays.
This original article is commented by Cohen and Lerman-Sagie on pages558–559 of this issue.
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