The inductive effect is one of the very important concepts of electronic effects in organic chemistry. In traditional teaching methods, only the origin, transmission mode, and decay of the inductive effect are introduced briefly, which is not conducive to students' complete understanding of the inductive effect. This work developed a new method to…

The effectiveness of a formal charge method to draw Lewis structures that was developed by Curnow was studied quantitatively by direct comparison of two groups of students: one of which was taught the new formal charge method and another that was taught a traditional method. Students' marks on a common assessment were found to improve by…

The application of chemistry concepts in biological settings plays an important role in the interdisciplinary field of drug discovery and development. This is true for molecular docking, where an understanding of intermolecular forces and noncovalent interactions is useful for rational drug design and development. Here we report the design and use…

The main difficulty in studying molecular symmetry is the mental manipulation of molecules when searching for symmetry. Numerous methods of teaching molecular symmetry require students to identify symmetry elements of objects or molecules. As an alternative, we propose activity that identifies symmetry using elements outside the objects, together…

Development of three-dimensional (3D) printing technology has started a new chapter for in-classroom modeling of chemical molecules. The technology provides the opportunity to design and produce various types of personalized models. However, using classical 3D printers is time consuming, and it is hard to involve students in the modeling process…

In this paper, we develop a general but very simple mathematical foundation for the predefined coefficient graphical method of Hückel molecular orbital theory (HMO). We first present the general solution for the recurrence relation of the coefficients of Hückel molecular orbitals (MOs). Subsequently, for all the three unbranched hydrocarbons,…

The point particle is an idealized object where rotational and vibrational motion is ignored. Nevertheless, in many cases such degrees of freedom play a significant role. For example, the rotation and vibration of a molecule is an important "reservoir" of its internal energy. The excitation of these types of motion can occur during the…

The aim of this study was to develop molecular genetics inquiry programs using the "eyes absent" gene of "Drosophila melanogaster." The program was composed of various molecular genetics experiments, including mutation observation, cross-breeding, searching for genetic information in web databases, gDNA extraction, and PCR.…

The integrated curriculum was recently introduced to the foundation medical education in Chinese medical schools. In this context, Wuhan University has offered two integrated courses, ie., Cell, Molecule and Genes (CMG) and Tissue and Function (TF). The purpose of this paper is to unfold problems in the design and implementation of integrated…

A structured series of activities has been designed and implemented to promote analysis and data reporting skills for second-year organic chemistry students. Student report sheets were developed to assist students in reporting necessary data for their compounds. A series of rubrics have been utilized by students to promote metacognition and by…

We propose an innovative approach to teaching friction. Our approach aims to educate students on its microscopic nature by highlighting its origin in intermolecular interactions. We have designed a teaching sequence (TS) based on a set of experimental investigations of the properties of a gecko-inspired tape at different length scales. The TS has…

Concept mapping remains widely used in education. However, little is known about how self-constructed concept maps and peer feedback can improve student learning outcomes in chemistry. We investigated the effects of peer feedback on concept mapping and how it improves students' learning performance in a large second-semester, introductory…

Being able to move between different representations levels (macroscopic, submicroscopic, and symbolic) is important to understand a chemical phenomenon meaningfully. The current study investigated how pre-service science teachers moved from symbolic representation to sub-microscopic representation. A total of 205 pre-service science teachers,…

Different molecular representations are usually used to depict the three-dimensional (3D) structure of organic compounds. Mastering the skill of interconverting one form into another is essential for students to ensure success in organic chemistry. The traditional and recently developed methods for completing such interconversions that rely on 3D…

An integrated system comprising a commercial high-performance liquid chromatography HPLC (except autosampler) equipped with an external multichannel autofeeding module was developed to accomplish interference-free separation and kinetic tracking for the H[subscript 2]O[subscript 2]-thiourea reaction, which is proposed as a lab experiment for…