Discusses major uses of rats as experimental animals for studying health concerns, pointing out that their size, gestation, and histocompatibility make them useful in various studies. Topic areas addressed include aging, autoimmune disease, genetics, cancer, diabetes, hypertension, infection, reproduction, and behavior. (DH)

This booklet, geared toward an advanced high school or early college-level audience, explains how structural biology provides insight into health and disease and is useful in developing new medications. This publication contains a general introduction to proteins, coverage of the techniques used to determine protein structures, and a chapter on…

After considering several different methods, it was concluded that primary journals for coverage of a given field can be selected rationally on the basis of their citation frequencies in an appropriate secondary journal. Library coverage of any particular field, thus, can be specified as a function of its budgeting commitment. (25 references)…

Reports findings of a study of the 10-year use of 334 biomedical journals in the Lane Medical Library of Stanford University Medical Center. Use and density of use (use/shelf space occupied) statistics are tabulated and a ranked list of the journals, by use and use-density, is appended. (JD)

Relying upon grant-supported salaries, many medical schools have greatly expanded their faculties; but if new funding devices are not discovered, retrenchment will occur. Physicians, who are trained to look at the big picture, must continue to be an essential element in the biomedical research team. (MLW)

A professor of epidemiology at the University of Pittsburgh tracks the fiscal fortunes of the National Institutes of Health. Any tightening of the NIH budget might starve out talented young researchers at Pittsburgh. Support from the agency amounts to about half of all government support. (MLW)

Describes the SAPHIRE (Semantic and Probabilistic Heuristic Information Retrieval Environment) that was developed to identify optimal approaches to indexing, retrieval, and evaluation of information retrieval systems in the biomedical domain. Six evaluation studies that have been done with SAPHIRE are summarized and future challenges are…

An African-American researcher is spearheading a black biomedical research movement to urge more African Americans to investigate the health issues affecting their communities. His research focuses on the acquired immune deficiency syndrome (AIDS) virus, but he is encouraging general expansion of the black researcher population. (MSE)

Examines the structure of medical informatics and the relationship between biomedicine and information science and information technology. Uses co-occurrence analysis of subject headings assigned to items indexed for MEDLINE as well as multidimensional scaling to show seven to eight broad multidisciplinary subject clusters. (Contains 28…

Marion D. Francis and Rosemary L. Centner tell the story of a special group of compounds, developments at their home company, Procter and Gamble, and contributions by researchers in Europe and the U.S., in "The Development of Diphosphonates as Significant Health Care Products."

Objectives: To report the findings of a literature review of the concept of wellbeing and consider its operational and heuristic potential within a range of disciplines. Design: A literature review to examine the philosophical roots of wellbeing and the contributions of the main disciplines uncovered by the review; economics, psychology, health…

Eighty-three teachers across the curriculum were interviewed to explain their views on and approaches to, the teaching of socio-scientific controversial issues to 14-19 year olds, particularly with regard to developments in biomedicine and biotechnology. This study focused on teachers' views on the nature of evidence in controversial issues and…

While there is sufficient evidence to suggest that physical activity is inversely related to lifestyle diseases, researchers are far from being certain that this evidence extends to children. Nevertheless, the school physical education curriculum has been targeted as an institutional agency that could have a significant impact on health during…

A case is made for directly relating biomedical research to national health service revenues. We are headed for "stultification and possible disaster" if we do not. (Author/RH)