Medical research is held as a field for education to emulate. Education researchers have been urged to adopt randomized controlled trials, a more "scientific" research method believed to have resulted in the advances in medicine. But a much more important lesson education needs to borrow from medicine has been ignored. That is the study…

Video ethics in educational research involving children is a recent topic that has arisen since the increase in the use of visual mediums in research (such as photovoice and video) especially with the development of new and ubiquitous internet technologies and social media. This paper emerged as an expressed concerned by a group of scholars…

Meta-analyses often include only a small number of studies ([less than or equal to]5). Estimating between-study heterogeneity is difficult in this situation. An inaccurate estimation of heterogeneity can result in biased effect estimates and too narrow confidence intervals. The beta-binominal model has shown good statistical properties for…

Background: Multivariate meta-analysis (MVMA) jointly synthesizes effects for multiple correlated outcomes. The MVMA model is potentially more difficult and time-consuming to apply than univariate models, so if its use makes little difference to parameter estimates, it could be argued that it is redundant. Methods: We assessed the applicability…

Network meta-analysis (NMA) uses both direct and indirect evidence to compare the efficacy and harm between several treatments. Structural equation modeling (SEM) is a statistical method that investigates relations among observed and latent variables. Previous studies have shown that the contrast-based Lu-Ades model for NMA can be implemented in…

School-based research presents ethical challenges, especially with respect to informed consent. The manner in which pupils and their parents respond to an invitation to participate in research is likely to depend on several factors, including the level of trust between them and the researchers. This paper describes our recruitment and consent…

Offering high school students' exposure to university level laboratory research encourages interest in science, develops critical thinking, and prepares the new generation for college and careers. In this study, we report on the development of an immersive 2-week summer camp with the aim of training high school students in cancer research.…

Course-based undergraduate research experiences (CUREs) can engage large numbers of students and provide a structured environment in which to learn valuable research skills. The ability to implement laboratory-based CUREs was hindered by the COVID-19 pandemic, generating a greater need for online options. A pilot study of an adaptation of a fully…

According to national labor market information study, access to talent is the greatest business challenge Canadian biotech companies are facing. We, therefore, developed, implemented, and assessed a pharma industry-inspired, medicinal research laboratory module in an experiential capstone biotechnology laboratory course. This involves developing a…

There is a gap in evidence regarding how research trial closure processes are managed to ensure continuity of HIV care for HIV positive participants following trial closure within low income settings. This research aimed to establish how research staff in Uganda understood and practised post-trial care for HIV positive trial participants. A…

Today, most medical research depends on statistics, and interpreting these is crucial as the world tries to improve health outcomes. Medical students are at the front line in this effort but many have negative attitudes toward statistics. To assess this and offer recommendations, this study evaluates the attitudes of medical students in Riyadh,…

Proposed changes to the Common Rule are proffered to save almost 7,000 reviews annually and consequently vast amounts of investigator and IRB-member time. However, the proposed changes have been subject to criticism. While some have lauded the changes as being imperfect, but nevertheless as improvements, others have contended that 'neither the…

Efavirenz (EFV) is a well-known, effective anti-retroviral drug long used in first-line treatment for children and adults with HIV and HIV/AIDS. Due to its narrow window of effective concentrations, between 1 and 4 µg/mL, and neurological side effects at supratherapeutic levels, several investigations into the pharmacokinetics of the drug and its…

Time-course model-based network meta-analysis (MBNMA) has been proposed as a framework to combine treatment comparisons from a network of randomized controlled trials reporting outcomes at multiple time-points. This can explain heterogeneity/inconsistency that arises by pooling studies with different follow-up times and allow inclusion of studies…

Background: Medical research on children has increased in the last 20 years. International ethical regulations for conducting clinical research on children may not pertain to Muslim communities where religious beliefs play a big role in decision-making process. Methods: The aim of this paper was to illustrate the origins of bioethics principles in…