The polysialylated neural cell adhesion molecule (PSA-NCAM) has been implicated in activity-dependent synaptic remodeling and memory formation. Here, we questioned whether training-induced modulation of PSA-NCAM expression might be related to individual differences in spatial learning abilities. At 12 h posttraining, immunohistochemical analyses…

It is well established that the cerebellum and its associated circuitry are essential for classical conditioning of the eyeblink response and other discrete motor responses (e.g., limb flexion, head turn, etc.) learned with an aversive unconditioned stimulus (US). However, brain mechanisms underlying extinction of these responses are still…

Motor learning in the vestibulo-ocular reflex (VOR) and eyeblink conditioning use similar neural circuitry, and they may use similar cellular plasticity mechanisms. Classically conditioned eyeblink responses undergo extinction after prolonged exposure to the conditioned stimulus in the absence of the unconditioned stimulus. We investigated the…

Neural networks are applied to a theoretical subject in developmental psychology: modeling developmental transitions. Two issues that are involved will be discussed: discontinuities and acquiring qualitatively new knowledge. We will argue that by the appearance of a bifurcation, a neural network can show discontinuities and may acquire…

Early deprivation causes serious disruption in the development of brain architecture and in the behaviors related to the affected brain functions. Some brain structures, and the broad categories of development that depend on them, show more "plasticity," or sensitivity to disruption and intervention for longer periods of time, than…

Inflammation during the perinatal period has become a recognized risk factor for developmental brain injuries over the past decade or more. To fully understand the relationship between inflammation and brain development, a comprehensive knowledge about the immune system within the brain is essential. Microglia are resident immune cells within the…

Successful treatment of many childhood diseases once considered terminal has resulted in the emergence of long-term effects of the disease or consequences of treatment that were previously unrecognized. Many of these long-term effects involve the central nervous system (CNS) and are developmental in the way that they emerge over time. Because we…

In this article, the author discusses several research reports demonstrating the existence of sex differences in cognitive function and language skills. Although dozens of studies published in the past five years have demonstrated dramatic sex differences in autonomic function, the educational literature has not emphasized those studies and their…

This book describes a neuro-developmental approach to learning difficulty assessment and remediation through assessment of a student's reception of information through the sensory channels, processing of sensory information in the brain, and repertoire of responses for expression. Chapter 1, "Reflexes: Their Impact on Success or Failure in…

A study investigated how Accelerated Learning (AL), a teaching methodology that purports to increase the quantity and improve the quality of learning, affected tertiary students' knowledge of and skills in writing and their feelings towards writing. AL has its origins in G. Lozanov's "suggestopedia." Believing that formal teaching…

This report documents research and development performed under the sponsorship of the Cognitive and Neural Sciences Division of the Office of Naval Research in fiscal year 1991. It provides abstracts (title, principal investigator, project code, objective, approach, progress, and related reports) of projects of three program divisions (cognitive…

The dichotomy of language acquisition versus language learning is critically examined by comparing the concepts presented in Krashen's Monitor Model and Stevick's Levertov Machine to information from the field of neurophysiology regarding the brain's processes. It is proposed that support exists for the theory that two very different processes…

A study examined laterality effects observed in previous studies in which men as well as right-handers show a right-visual field (RVF) advantage for letter recall and a left-visual field (LVF) advantage for letter position recall, suggesting asymmetrical brain organization for these groups. Subjects, 96 undergraduates equally divided by sex and…

An attempt is made, using a partial review of the literature, to present a non-technical overview of some of the child-related issues in simultaneous bilingualism. While controversy still rages in the area of bilingualism research, some definite changes can be discerned over the past 40 years. Opinion has shifted from a deficiency perspective to…

Neuropsychology is an area in which the functioning or integrity of the brain is linked to measurable human behavior. This paper describes the use of the Reitan batteries (Reitan and Davison; 1974) in public school settings for documenting and prescribing appropriate academic programs. Three individual case studies are presented. Case 1 is a 16…