This paper discusses the results of two learning disabilities investigations conducted at the Yale Center: (1) research from longitudinal studies on the development of children not identified as having a disability and (2) neurobiological studies that employ functional magnetic resonance imaging. Other ongoing studies at the center are also…

An interview with Dr. Shaywitz , pediatrician, neuroscientist, and member of the National Reading Panel, focuses on the ways the brains of young children develop and what can be done to prevent early learning difficulties. (MLF)

Three studies investigated whether anatomical measures could separate phonologically based reading disability (PD) from non-phonologically based learning disabilities such as specific language impairments (SLI) in children. Results indicate that PD and SLI are qualitatively different disorders associated with anatomical deviations in opposite…

A study provided specially designed hemisphere-specific stimulation (HSS) and hemisphere-alluding stimulation to 21 children categorized as P-type dyslexics (showing accurate but slow and fragmented reading) and 19 children categorized as L-type dyslexics (fast but inaccurate readers). Participants made gains on all reading measures, regardless of…

This article discusses findings concerning the plasticity of auditory cortical processing mechanisms in adults, including the effects of restricted cochlear damage or behavioral training with acoustic stimuli on the frequency selectivity of auditory cortical neurons and evidence for analogous injury- and use-related plasticity in the adult human…

A bird study found that with sufficient time and training after hair cell and hearing loss and hair cell regeneration, the mature avian auditory system can accommodate input from a newly regenerated periphery sufficiently to allow for recognition of previously familiar vocalizations and the learning of new complex acoustic classifications.…

Describes the author's research on learning and brain activity, which involved more than 5,000 students and faculty members. Explores six stages of learning: (1) preparing to learn; (2) starting to learn; (3) consolidation; (4) branching out; (5) gaining fluency; and (6) continued improving. States that merging educational research with…

Prior research suggests that when very simple event sequences are used, 4.5-month-olds demonstrate the ability to individuate objects based on the continuity or disruption of their speed of motion (Wilcox & Schweinle, 2003). However, infants demonstrate their ability to individuate objects in an event-monitoring task (i.e., infants must keep track…

A weakness in accessing the sounds of spoken language represents the most robust and specific correlate of reading disability in young school age children and adolescents. Neurological science and reading research that provides the scientific knowledge regarding this disability is presented.

The majority of children and adults with reading disabilities exhibit pronounced difficulties on naming-speed measures such as tests of rapid automatized naming (RAN). RAN tasks require speeded naming of serially presented stimuli and share key characteristics with reading, but different versions of the RAN task vary in their sensitivity: The RAN…

Neglect is an acquired cognitive disorder characterized by a lack of processing of one side of a stimulus or representational space. There are hemispheric asymmetries in its cause and in its effects, but implemented computational models of neglect have tended not to incorporate this fact. The authors report a series of neural network simulations…

Measuring the changes in neurotransmitter extracellular levels in discrete brain areas is considered a tool for identifying the neuronal systems involved in specific behavioral responses or cognitive processes. Acetylcholine (ACh) is the first neurotransmitter whose diffusion from the central nervous system was investigated and whose extracellular…

Despite their purported neuroanatomic and functional isolation, empirical evidence suggests that sometimes conscious explicit processes can influence implicit motor skill learning. Our goal was to determine if the provision of explicit information affected implicit motor-sequence learning after damage to the basal ganglia. Individuals with stroke…

Previous studies have indicated that nonhuman animals might have a capacity for episodic-like recall reflected in memory for "what" events that happened "where" and "when". These studies did not identify the brain structures that are critical to this capacity. Here we trained rats to remember single training episodes, each composed of a series of…

The goal of this work is to extend the theoretical understanding of the relationship between hippocampal spatial and memory functions to the level of neurophysiological mechanisms underlying spatial navigation and episodic memory retrieval. The proposed unifying theory describes both phenomena within a unique framework, as based on one and the…