Campus Mentors is a new career-based intervention (CBI) model that is located on a college or university campus. It was designed to address two needs: the need to provide additional support to the most at-risk secondary students, and the need to improve teacher preparation to serve these students. The model has four unique components, but can be adapted for each site. In this article, the authors describe the model, present outcomes, and outline promises and pitfalls; the intent is to assist local communities interested in establishing similar partnerships.