This chapter identifies some of the challenges facing the applied and workforce baccalaureate. The authors believe that it is important to discuss potential challenges regarding mission, institutional identity, and faculty for college leaders, practitioners, and policy makers to address when seeking to create or maintain applied and workforce baccalaureates. Their discussion in this chapter is based on the review of ideas that have already been documented in both the scholarly and practical literature, and it offers an illustration of those points with current developments and our perspectives about this degree. The authors seek not to argue against the baccalaureate but rather to identify concerns that need to be addressed in order to design and implement the degree effectively.