There is a national movement underway to assist teachers in connecting the ideas and practices found in multicultural, general, and special education (Sobel & Taylor, 2006, p.29). In particular, educators are seeking innovative ways to implements general education practices with students with low incidence disabilities. This article describes the model used by one elementary school teacher to implement guided reading, a research-based practice in a LIFE skills classroom in order to increase the reading skills of students with autism. The teacher shares how each student's reading levels were identified and describes the classroom management system that allowed for instruction based on student needs. The teacher's knowledge of the guided reading principles allowed the students to take responsibility for their learning, providing them with challenging reading lessons that lead to growth in their own reading abilities. Each component of the program can be replicated within a general or special education classroom.