The focus of this work is community-based participatory research (CBPR) and its relationship to historically Black colleges and universities (HBCUs). Using published literature, the authors make the argument that HBCUs are well-suited for this approach because of their origin and history, their community ties, and the commitment of faculty and students. A larger discourse regarding research at HBCUs is sought. The impact of this larger discourse should lead to more community engaged research at HBCUs and, most importantly, positive impact on the communities that are the focus of CBPR.