As America emerges from recession, certain industries are expected to grow particularly fast and will present many job opportunities for both young people and career changers. This article looks at these high-opportunity industries and the kinds of jobs they are expected to open up. In the global economy of the 21st century, many low-skill jobs can be done either by computers or by workers in low-wage countries. The American industries that remain competitive will be those that focus on what the nation does better than most other countries; creativity and innovation. But these do not happen by accident. They rest on three pillars: a highly educated workforce, a healthy workforce, and an outstanding infrastructure. All three of these pillars have been threatened over the last few decades, but the government has targeted them all for renewal, and each is associated with industries that will provide many jobs in the coming decade.