Community-based participatory research (CBPR) has emerged as an approach designed to promote community health and well-being through the establishment and maintenance of research partnerships between communities and academic researchers. Rather than the academic researcher assuming what is best for a community, CBPR utilizes community partnerships to establish full and equal participation in research by community members, organizational representatives, and academic researchers. CBPR emphasizes co-learning, reciprocal transfer of expertise, and sharing of decision-making power. In this article, we introduce CBPR within the context of rehabilitation research, outline some of the essentials for conducting a CBPR study, and apply CBPR in the research process. A CBPR case study is provided. (Contains 2 tables.)