Electrospinning has been used to create nanofibers for filtration devices, tissue engineering, and protective clothing. Although electrospinning is now widely studied, because of the expensive equipment required and the advanced nature of this topic, it is not commonly found in high school science labs. Through grants from the Ohio State University and the National Science Foundation (NSF), the author was able to obtain the necessary equipment and adapt it for use in the high school science classroom. This article describes the authors' experience with electrospinning in an 11th- and 12th-grade Honors Physics class. (Contains 3 figures and 1 online resource.)