Advanced generalist practice is the fastest growing area of concentration for Master of Social Work (MSW) programs in the United States, yet a definition remains elusive. This article proposes that three key elements should be included within a conceptual schema of advanced generalist practice. Multidimensional problem-setting, self-reflective leadership, and ethical advocacy form the basis of a model for advanced generalist practice. Discussion of the epistemology of advanced practice highlights the connection between advanced generalist practice and the experienced practitioner. Discussion regarding what makes practice advanced is presented and related to curriculum development.