Many students with Asperger's Syndrome have the cognitive ability and specific interests to be successful academically at the college level. However, these students often have difficulties navigating social systems, and higher education presents great challenges. The purpose of this study was to explore parent perceptions regarding the: (a) supports or accommodations college-bound students with Asperger's Syndrome need at the postsecondary level to successfully adjust to the academic and psycho-social expectations of the college experience, and (b) self-advocacy skills or strategies needed to increase the likelihood that students with Asperger's Syndrome be successful in college. Parents reported a variety of strategies that colleges can use to support students with Asperger's Syndrome within postsecondary settings and provided insights into their expectations for college-level supports. Implications for practice and recommendations for future research are discussed.