Through a new working group, tribal colleges and universities (TCUs) are playing a critical leadership role in addressing some of the most difficult climate-related problems now facing the planet. Because of their unique cultural character, TCUs have an important voice. The American Indian and Alaska Native Climate Change Working Group was formed in June 2006, and in the past two years, it has taken significant steps. It brought some of the nation's leading scientists together with some of Indian Country's most respected elders. Working with National Aeronautics and Space Administration (NASA) and the American Indian Higher Education Consortium (AIHEC), the tribal colleges have involved students in climate research in their own backyards. And they have begun training tribal college students to create digital films and documentary film archives about changes in landscapes and seascapes. The working group is a network of many organizations and individuals in which TCUs constitute the central nodes. The group includes federal agencies, national scientific centers, tribal and inter-tribal organizations, non-governmental organizations, and, more recently, private sector partners. This article describes how the working group emerged and discusses the working group's four major accomplishments.