Is it feasible and appropriate to develop a sustainability metrics which captures cosmological-spiritual dimensions of un/sustainability? Departing from the supposition that the crisis of unsustainability is a crisis of worldview and misguided cosmology which needs redirection on a cultural and global scale, this essay introduces the notion of a diagnostic instrument with which metaphysical aspects of un/sustainability may be assessed. Using the ecological footprint as a template, the essay proposes the "spiritual handshake" as a complementary analysis tool to ascertain the im/balance of personal self-interest versus goodwill and service to the common good. The paper outlines the conceptual foundations and metaphorical content of the spiritual handshake, suggests a set of assessment indicators, and applies the tool to a case study: that of the Terminator Gene. (Contains 2 tables and 5 figures.)