Background: Exercise is important for health and well-being. The aim of this study was to investigate the effect of physical training on general well-being and self-image in older people with intellectual disability. Methods: This study evaluated older adults with intellectual disability in residential care in Israel. The concept of well-being perceived by the participants was measured by direct interview with a questionnaire consisting of 37 structural statements. The physical training programme was conducted three times a week for 10 consecutive months. Results: Statistical analyses suggested a positive relationship between perceived well-being and physical training between the experimental and control group. Conclusions: This positive relation supports the important role of physical training to improve perceived well-being among older adults with intellectual disability.