Objectives: Psychometric properties of the Chinese version of the Interpersonal Reactivity Index (C-IRI) for the assessment of empathy in Chinese people were examined. Method: The Interpersonal Reactivity Index (IRI) was translated to Chinese, and an expert panel reviewed its content validity and cultural relevance. The translated instrument (C-IRI) was administered to 189 junior high school students and 391 university students. Results: Confirmatory factor analyses revealed a stable hierarchical three-factor structure that was consistent with structure of the English IRI, but the cognitive and emotional aspects of empathy were combined to form a new factor. The subscales of the C-IRI demonstrated acceptable to good internal consistency and test-retest reliability. Some evidence for the construct validity of the measure was also found. Conclusions: The C-IRI possessed acceptable psychometric properties in Chinese adolescent samples. The present findings suggest that the cognitive and emotional aspects of empathy are not differentiated in Chinese adolescents. (Contains 1 figure and 3 tables.)