African American infants have higher rates of child welfare system involvement than any other demographic group. They are overrepresented at every point on the child welfare continuum, from reporting, to substantiation, to foster care placement, to adoption. Racial disparities have also been noted in the services these children receive. This article reviews the evidence on the experiences of African American children in the child welfare system, with a particular focus on infants. The author provides policy and practice recommendations to reduce racial disproportionality and to address the unique needs of African American infants.