Drawing upon construal level theory, this research investigates the influence of social distance on individuals' responses to persuasive messages. Experiment 1 (N = 133) demonstrates that the persuasive impact of a gain frame becomes stronger when people make judgments for socially distant (e.g., others) versus proximal entities (e.g., selves). On the other hand, the persuasive impact of a loss frame remains the same across different levels of social distance. Experiment 2 (N = 135) shows that the persuasiveness of a societal frame becomes stronger when people make judgments for socially distant versus proximal entities, whereas the persuasiveness of an individual frame is unaffected by social distance. Experiment 3 (N = 80) provides evidence that mental salience of positive and societal outcomes of an action increases as social distance increases, whereas mental salience of negative and individual outcomes remains the same across different levels of social distance.