Teaching literacy to struggling readers can present many challenges. This article suggests 10 strategies that can help middle and high school language arts and content area teachers meet them: (1) Ask for help; (2) Support word recognition needs; (3) Select appropriate materials; (4) Develop reading fluency; (5) Foster vocabulary acquisition; (6) Build comprehension; (7) Monitor student progress; (8) Differentiate instruction; (9) Group students effectively; and (10) Embrace more flexible ideas about reading materials.