The discussion of the gap between theory and practice has a long tradition in educational psychology and especially in research on learning and instruction. Starting with a short analysis of more or less elaborated approaches focusing on this problem, a complex procedure called "integrative research approach", specialized in reducing the gap between basic and applied research, is described in detail. After addressing the starting point and goals of integrative research, the guiding principle, methodological procedures, as well as theoretical and methodical implications are discussed. All characteristics of the integrative approach are exemplified by our own research projects in the domain of economics and medicine. In the outlook, strengths and weaknesses of this approach are discussed and some consequences are drawn to increase the sustainability of implemented instructional innovations.