Brief experimental analyses were conducted using two dependent variables to evaluate the effectiveness of reading interventions. Specifically reading rate (words read correctly per minute) and mean reading comprehension levels for six students with reading difficulties were obtained using six different reading intervention/intervention combinations. These interventions included contingent reinforcement, listening passage preview, repeated reading, listening passage preview with contingent reinforcement, repeated reading with contingent reinforcement, and repeated reading with listening passage preview. Results suggested that no one intervention was best for all students. In addition, it was found that interventions that increased reading rate for half of the students also increased reading comprehension for the same students. Discussion focuses on student-treatment interactions, measuring student reading performance, matching treatments to students, and directions for future research.