Retinitis pigmentosa (RP) is a degenerative disease of the retina that causes the severe impairment of visual functioning similar to low vision, leading, in many cases, to blindness. Because the construct of self-concept plays a key role in personality, this study was designed to measure self-concept in a group of young adults with RP. The participants were 45 Caucasian adults aged 19-35, who were studied in two groups: 22 people with RP and some residual vision who had no other impairments and had been diagnosed with RP at least three years before the study, and 23 with no known visual impairment. The participants were matched for age, level of education, marital status, and gender. The Tennessee Self-Concept Scale which consists of 100 self-descriptive items that are classified in five subscales that evaluate specific components of self-concept: personal, family, moral-ethical, social, and physical self was used. The data for both groups were compared with an appropriate t-test for differences of the means for independent groups depending on homoscedasticity. Mean scores and standard deviations were calculated for each self-concept subscale for the two groups. Results showed that participants with RP scored significantly lower on the family self-concept subscale, but no significant differences were found in the moral-ethical; physical; personal; or social self-concept subscales. The lower scores for family self-concept indicated that the participants with RP rated themselves poorly as members of their families, were unsatisfied with their family members, or showed signs of not feeling well loved by others in their immediate family circle. This finding points to the need for intervention programs to help people with RP and their families to improve their personal well-being and the quality of their communication and relationships. Because of the limitations this study had, additional studies are recommended to confirm the findings.