The "comadre" approach to group counseling with immigrant Mexican women creates an environment of sisterhood, trust, support, and education. This article describes a wellness-based, comadre pilot group designed to support monolingual Spanish-speaking, Mexican-born women who recently immigrated to the United States. The need for the group and group development and process are described. The 10-week pilot group is described illustrating this particular comadre model of group work with immigrant Mexican women. Implications for future group work and research with Mexican female immigrants are discussed, and suggestions are offered for wellness-based group work led by cross-cultural counselors.