Unless the teacher is working at an ergonomically designed workstation, using a computer can result in eyestrain, neck aches, backaches, and headaches. Unfortunately, most teachers do their keyboarding at desks, on lab tables, and in other spaces that were not designed with computer use in mind. Ergonomics is the science of adapting workstations, tools, equipment, and job practices to be compatible with the individual worker and thus reduce the possibility of injury. Lab-based science instruction requires teachers to perform many repetitive tasks, such as writing on the chalkboard, using a microscope, keyboarding, and pipetting, which can lead to aches and pains. However, many common problems can be avoided if teachers become aware of their work environment and avoid certain behaviors. This article offers some of the more common ergonomic-related hazards of working in the lab and suggestions for avoiding them.