Having lived through the Great Depression and World War II, older adults now face the challenge of vision loss in record numbers. Depression is closely associated with functional loss and social isolation in late-life vision loss. The principles of assisting those who are aging will also benefit those who are aging with a visual impairment. They include recognizing depression, addressing multiple health concerns, promoting well-being, using a client-centered approach, and working collaboratively with the medical community and aging network.