U.K.'s Teaching and Learning Technology Programme (TLTP) developed a General-Purpose Integrated Learning Support (G-PILS) tool-kit and shell. G-PILS creates course/module specific learning support systems to manage the integration of courseware in a range of knowledge media (e.g., games, tutorial packages, simulations, electronic documents, interactive presentations) within tailored environments. Evaluation of three such systems in pharmacology is discussed. (Author/AEF)