Our purpose is to highlight the contributions of TalkBank initiatives to improved understanding of clinical impairments in adult and child speakers and examine remaining challenges and proposed solutions. We review the origins and development of TalkBank initiatives that have targeted a wide array of typical and atypical child and adult populations. In particular, we discuss how such sets of data have given rise to evaluation and validation of traditional measures used to appraise spoken language performance. The durable contributions of AphasiaBank and CHILDES archives are already evident in a body of published research that has re-evaluated, refined and reconceptualized how we evaluate and set therapeutic goals for speakers with expressive speech and language impairments. More recent archival initiatives, such as PhonBank and FluencyBank, are also making impacts. Beyond improvements in basic and applied science in communication development and disorders, archival data are also being used to test and improve accessibility for communicatively impaired speakers. TalkBank has transformed how research in communication disorders is conducted. It no longer relies on small, unshared research ventures that enable limited clinical impact or follow-up research inquiries. Rather, it has enabled largescale, more generalizable research more likely to spur further research and enable more rapid translation to clinical practice.