Science teachers struggle to implement and sustain new curricular ideas from professional development (PD) experiences. These PD opportunities are crucial for enacting real-world changes to teaching practice and address pressing global challenges, such as the teaching and learning of socioscientific topics nested in school communities. Additionally, it is important to consider how school situative conditions are an important aspect in how science teachers learn, develop, and enact curricular practices in their classrooms. This paper is part of a special issue on "Teacher Learning and Practice within Organizational Contexts." The purpose of this conceptual paper is to illustrate how researchers can frame research using the theory of practice architectures (TPA) as a lens to develop a dynamic socio-material understanding of teacher learning within teachers' working environments and their local school communities. An ongoing multi-year professional learning study with science teachers in an elementary school and secondary school was analyzed using TPA. Using a philosophical-empirical approach, observations from PD sessions and collaborative meetings illustrated teachers' practices in the form of sayings, doings, and relatings and their changes over the duration of the observations with associated modifications in schools' practice architectures. Although specific school conditions, such as timetable restrictions and curriculum accountability, constrained teachers' practices they were still enabled to learn and develop their practices. Overall, TPA was found to be an insightful framework for theorizing changes in science teaching practices of teachers' saying, doings, and relatings at their school sites. Future research focused on PD within schools would benefit from using a TPA approach to theorizing science teacher learning and curriculum enactment practices.