With the advent of new technologies, cases of online child sexual abuse have become notoriously widespread, rendering it necessary for both teachers and parents to know how to deal with this phenomenon. The aim of this study was to find out which were the main interventions and strategies that both teachers and parents could apply within their immediate environment to reduce the risk of online child sexual harassment. Using the PRISMA approach for systematic reviews, all literature about strategies and interventions for reducing the risk of online child sexual abuse from a variety of databases was analyzed. When possible, Cohen's d was used to measure the effect size of the interventions. Based on 38 included papers out of a total of 5644, it was found 13 strategies that teachers could commonly use with their students, such as reading real-life testimonies of grooming, as well as 7 strategies that parents could commonly use with their children, such as establishing rules about the use of the internet. The effect sizes showed a reduction in the prevalence of grooming [Experimental (d = -.71 to .03); Control (d = .00 to .50)] and an increase in knowledge and attitudes [Experimental (d = .45 to 1.66); Control (d = -.03 to .22)] in favor of the students that participated in the interventions. The present results suggest that using these kind of interventions and strategies may bring positive results for children and teenagers in order to prevent and cope with online child sexual abuse