Entrepreneurship has become a central issue in an effort to improve the nation's economic welfare. Several previous studies agree that the ideal country is one that has an entrepreneurial contribution of at least 4% of its total population. However, when compared with other countries, Indonesia's entrepreneurial contribution is currently still low because it has only reached an entrepreneurial ratio of 3.47%. One of the causes of this low contribution is the lack of effective entrepreneurship education. Some empirical evidence has not been able to explain how entrepreneurship education is able to prepare generation Z to become entrepreneurs through various new literacies. This research aims to investigate the influence of entrepreneurship education on the entrepreneurial readiness of generation Z students, which is moderated by digital business literacy and financial literacy. This research was conducted using a quantitative approach and involved 700 students in Makassar City, Indonesia. The data analysis technique used is partial least squares structural equation modeling (PLS-SEM) analysis. Research findings show that entrepreneurship education plays an important role in the entrepreneurial readiness of generation Z students, which is strengthened by digital business literacy and financial literacy. The findings of this research can help expand and develop concepts related to digital business literacy and financial literacy in the context of entrepreneurship education in higher education, so that, by implication, this research provides a valuable contribution to entrepreneurship education, which paves the way for further research regarding entrepreneurial readiness in the context of diverse higher education through various other new literacies.