The study aims to investigate the mediating role of output, productivity, and outcome variables in the relationship between input or process variables and research performance. By examining how these variables interact, the study aims to enhance our understanding of the factors that influence research performance. This role was investigated using the bootstrap method to calculate the indirect effects of the four developed models. Furthermore, the Hayes' Process macro SPSS Model 6 was applied to process the results of surveys and investigations of 150 research directors at Indonesian universities. The experience of these directors in conducting and managing research in the universities was used as high-quality and accurate information. The results showed the output, productivity, and outcome variables act as partial mediators in the relationship between inputs and processes on research performance. Therefore, this study theoretically and practically contributes to the implementation of policies in evaluating research performance in universities institutionally, nationally, and globally.