The aim of this article is to improve physical education (PE) teachers' knowledge about working with children diagnosed with cancer. Physical activity (PA) in this population is extremely important. Not only do these children have an increased risk of co-morbidities compared to healthy peers, but cancer treatment has negative effects on fitness (e.g., loss of muscle mass, impaired balance, cardiac dysfunction). A cancer diagnosis can delay motor-skill development and hinder the development of self-efficacy in sport and activity. PA can be used to attenuate treatment side effects and help children to build fitness, stamina, and confidence, enabling them to (re)join sport or group PA. Using data from a feasibility study, frequency, intensity, time, and type (FITT) recommendations are provided for children undergoing cancer treatment that provide a framework for educators to design action plans.