In parallel to web evolution from 1.0 to 4.0 with trends to 5.0, e-learning has evolved to smart learning (SmL). E-courses are pedagogically designed and implemented using web technologies to provide smart learning affordances (SLAs). By following research-based design methodology, this study investigates the effectiveness of web technologies integration into a meaningful e-learning 3.0 environment, aiming at SmL. An e-course was pedagogically designed, implemented by integrating 35 web technologies, and evaluated by three independent e-learning experts using the technology integration matrix (TIM) framework, oriented towards meaningful learning (ML). Results showed that such integration enhances the effectiveness of the delivered e-course. The e-learning environment proved authentic, at least active, constructive, and goal-directed (GD), yielding corresponding SLAs; however, it failed to prove collaboration due to most web technologies limited collaborative opportunities provided. Additionally, 15 web technologies were prominent. Findings provide guidelines for web technologies integration and insights for future work.