E-learning modules were developed to enhance student engagement, reflection and interdisciplinary learning in Pathology courses undertaken by students from the Biomedical Science, Allied Health, and Complementary Medicine disciplines. The modules focused on generating multi-disciplinary and team-based solutions to diagnosis, prognosis and treatment/management of patients. At pre- and post-intervention, we analysed the students' experience of three themes: E-learning, reflection, and interdisciplinary learning. Flexibility and ability to reinforce understanding of course content were identified as main advantages of e-learning but a lack of direct support was a common concern. Visual aids and interactive assessments were suggested to improve online experiences. While all students had a positive pre-conception of all themes prior to intervention, the delivery of the modules significantly improved students' perception on how e-learning deepened their understanding of course materials via reflection and interdisciplinary learning, with both aspects serving to create a holistic learning experience.