Teachers' roles are dynamic among all the factors contributing to educational achievements. Teachers' performance is an important factor associated with policy implementation and organizational outcomes. This article elicited the teachers' perceptions of fundamental factors affecting the teaching profession. The study conducted a focus group interview and analyzed it. A list of indicated factors was prepared and corroborated with existing literature. An online survey was conducted, and participants were asked to rank these suggested factors in order of priority for amelioration to sustain the teaching profession. The interdependence of preferences in identified seven critical areas was tested through teachers' demographics. The finding discussed factors affecting the teaching profession, including current issues in Pakistan's education sector. This study illustrates factors for prioritizing policy reforms through teachers' insights.