ERIC Number: EJ1445149
Record Type: Journal
Publication Date: 2023-Dec
Pages: 7
Abstractor: As Provided
ISBN: N/A
ISSN: ISSN-0021-9584
EISSN: EISSN-1938-1328
Multichannel Feeding Module-HPLC Integrated System for Online Species Tracking and Kinetic Analysis
Ying Hu; Weifan Chen; Chen Ji; Mengzhen Xu; Changwei Pan; Qingyu Gao
Journal of Chemical Education, v100 n12 p4721-4727 2023
An integrated system comprising a commercial high-performance liquid chromatography HPLC (except autosampler) equipped with an external multichannel autofeeding module was developed to accomplish interference-free separation and kinetic tracking for the H[subscript 2]O[subscript 2]-thiourea reaction, which is proposed as a lab experiment for students who have the background of chemical kinetics. Compared to conventional HPLC, the proposed system: (i) provides a similar pedagogical purpose, where students' knowledge in chemistry can be strengthened and improved and (ii) enables online species tracking and kinetic analysis of reactions with the spectral overlap of multiple species, and other interference factors such as turbidity caused by precipitation formation, bubble requirement, or external excitation light for photocatalysis. Additionally, automation of the proposed equipment allows for saving labor and high efficiency. Based on the reliability and accuracy of the proposed system, different species including reactants, intermediates, and products were simultaneously tracked during thiourea oxidation. Both kinetic curves of multiple species and kinetic parameters obtained provide lots of reliable data for fitting and mechanistic analysis. Because the H[subscript 2]O[subscript 2]-thiourea reaction as a lab experiment successfully performed by students with this technology has proven its operability for undergraduates majoring in chemistry, this proposed method is easy to extend to environmental science, pharmacokinetics, and other fields.
Descriptors: Undergraduate Students, Chemistry, Science Instruction, Kinetics, Molecular Structure, Laboratory Experiments, Technology Integration, Technology Uses in Education, Test Reliability, Science Achievement
Division of Chemical Education, Inc. and ACS Publications Division of the American Chemical Society. 1155 Sixteenth Street NW, Washington, DC 20036. Tel: 800-227-5558; Tel: 202-872-4600; e-mail: eic@jce.acs.org; Web site: http://pubs.acs.org/jchemeduc
Publication Type: Journal Articles; Reports - Descriptive
Education Level: Higher Education; Postsecondary Education
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A
Grant or Contract Numbers: N/A