Using telehealth technology to deliver parent training in evidence-based intervention has been suggested to increase the accessibility of such interventions and improve skill acquisition and generalization. Within behavior analysis, global restrictions in response to the COVID-19 pandemic highlighted the need for the development of telehealth supports for families. The current research examined the online delivery of a parent-mediated implementation of the Preschool Life Skills program (PLS). Four parents completed the parent PLS program with their typically developing children (aged 3-5 years) via weekly videoconferencing sessions. A multiple-probe experimental design was employed to assess the effect of the intervention on children's preschool life skills and challenging behavior. Parental embedding of PLS strategies during daily activities was also evaluated. The results demonstrated increases in children's preschool life skills, decreases in challenging behavior, and evidence of parent acquisition and use of PLS strategies.