This study attempts to provide a comprehensive overview of criteria for making a significant contribution to the body of knowledge. Authors propose a unique perspective of viewing such contributions as a combination of art and science, focusing on specific criteria such as rigor and relevance, novelty and originality, unity and form. While science-related criteria are based on formal logic and scientific methodology, equally important art-related criteria are based on creativity and congruency. The proposed classification may be useful for both academics and practitioners representing various disciplines. It provides researchers with a practical recipe for making significant contributions to the body of knowledge and offers a way to understand better and evaluate such contributions. Additional essential ingredients such as quality, balance, and timing are also discussed.