The purpose of this study is to investigate differences between women and men in chemistry, as reflected in their responses to a global gender gap survey. The survey was conducted in 2018; responses from 1,343 valid participants across the globe were collected and analyzed. The main results show that first, women were more likely to list their parents and themselves as important influences in their university studies than men. This result was consistent regardless of the Human Development Index (HDI, an index developed by the United Nations assessing the development of a country) and employment sectors. Also, men students reported more positive relationships and support from their advisors or supervisors than women. More women than men indicated that they had personally encountered sexual harassment at school or work. Also, in general, more men than women indicated that they had never experienced discrimination in the assessment or evaluation of their achievement across different HDI regions and in different employment sectors. Men reported having more research resources than women. More women than men indicated that their careers had influenced their decisions about their children, marriage, or long-term partnership across high and low HDI regions and employment sectors. Finally, women submitted fewer journal articles than men in the past five years, and this gender difference was also seen in respondents from both high and low HDI regions and working in industry. In contrast, by employment sector, the gender differences were relatively small.