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ERIC Number: EJ1442675
Record Type: Journal
Publication Date: 2022-Nov
Pages: 8
Abstractor: As Provided
ISBN: N/A
ISSN: ISSN-0021-9584
EISSN: EISSN-1938-1328
A Pedagogical Introduction to Biomarker Detection in Surface-Based Biosensors
Praneet Prakash; Manoj Varma
Journal of Chemical Education, v99 n11 p3694-3701 2022
The field of biosensors is a burgeoning area of research and employs a large number of chemistry graduates. The impact of strip tests in detecting coronavirus was palpable during the recent COVID-19 pandemic and will further drive the biosensor industry. Despite their common usage, a coherent introduction to the basics of sensing remains missing from the chemistry curriculum. Through this work, key concepts of transport and noise interference in molecular sensing aimed at upper-level coursework are introduced. Exercises including teamwork activities are proposed for teaching and inquiry-based learning. The presented approach was effective in solidifying the concepts of molecular transport and competing binding kinetics. Furthermore, students are introduced to an online database on biomarkers and open-source binding affinity resources. The material can be seamlessly integrated into the existing coursework by expanding discussions on binding kinetics and equilibrium.
Division of Chemical Education, Inc. and ACS Publications Division of the American Chemical Society. 1155 Sixteenth Street NW, Washington, DC 20036. Tel: 800-227-5558; Tel: 202-872-4600; e-mail: eic@jce.acs.org; Web site: http://pubs.acs.org/jchemeduc
Publication Type: Journal Articles; Reports - Descriptive
Education Level: Higher Education; Postsecondary Education
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A
Grant or Contract Numbers: N/A