Undergraduate research is an important experience that increases retention, ownership, and learning. Integrating research experiences into the classroom is the focus of course-based undergraduate research education (CUREs) and has become an important tool in curricula of many universities. This article will serve as a guide for those interested in starting a CURE. Information on the makeup of CUREs and a suggested workflow to design a CURE for chemistry disciplines is described. Examples of recent chemistry focused CURE examples and an introduction to supported CURE networks are described to help orient faculty interested in advancing their work as well as creating CUREs at large institutions and curricula that scaffolds CUREs at several levels.