The aim of the present cross-sectional study was to investigate the relationship between academic self-efficacy, life goals and subjective well-being of middle school students. The study group for the research comprised 434 middle school students. According to the findings, subjective well-being was correlated at a significant level with academic self-efficacy and life goals. Regression analysis revealed that academic self-efficacy and life goals significantly explained subjective well-being. The research findings provide important data about variables related to the subjective well-being of middle school students. Due to the research results, studies to increase academic self-efficacy and develop life goals for middle school students will contribute to increasing students' subjective well-being. For experts working in the field, the research findings will encourage the emergence of new research ideas related to other variables associated with the subjective well-being of middle school students.